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Sagarkumar Patel

30 papers indexed

openalexInternational Journal of Molecular Sciences2025-09-03Cited by 3

Musculoskeletal Complications in COVID-19: Exploring the Role of Key Biomarkers

Sagarkumar Patel, Cameron C. Foster, Kamal Patel, Monte Hunter, Carlos M. Isales, Sadanand Fulzele

The COVID-19 pandemic has revealed significant secondary complications affecting musculoskeletal (MSK) health, especially in patients with pre-existing conditions. This review synthesizes data from clinical and experimental studies on key MSK biomarkers, including cartilage oligo…

Also available via: Multidisciplinary Digital Publishing Institute

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openalexTelecom2025-06-16

Performance Analysis of Generalized Quadrature Spatial Modulation with Quasi-Orthogonal Space-Time Block Codes Under Nakagami m-Fading Channels

Sagarkumar Patel, Harishkumar B Chaudhari, Dharmendra Chauhan, Hardik Modi, Hiren Mewada, Sagar Kavaiya

Spatial Modulation (SM) is a promising technique for future wireless communication systems, as it reduces hardware cost and complexity while maintaining good bit error rate (BER) performance in MIMO systems. However, in real-world scenarios, systems often face challenges like ant…

Also available via: Multidisciplinary Digital Publishing Institute

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openalexIEEE Open Journal of the Communications Society2025-01-01Cited by 1

Toward Reliable and Efficient 6G Wireless Communication: A GQSM-QOSTBC-Based Spatial Modulation Framework

Sagarkumar Patel, Dharmendra Chauhan, Hiren Mewada, Harishkumar B Chaudhari, Sagar Kavaiya, Hardik Modi, et al.

This paper presents a new spatial modulation framework for future wireless communication networks by combining Generalized Quadrature Spatial Modulation (GQSM) with improved Quasi-Orthogonal Space-Time Block Codes (QOSTBC). The proposed detection method employs channel-matched fi…

Also available via: IEEE Communications Society

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openalexIEEE Access2025-01-01Cited by 18

Nation’s Defense: A Comprehensive Review of Anti-Drone Systems and Strategies

Dharmendra Chauhan, Harshil Kagathara, Hiren Mewada, Sagarkumar Patel, Sagar Kavaiya, Gordana Barb

The rapid advancement of drone technology has revolutionized both the civilian and military sectors, enabling a wide range of applications, from commercial deliveries to battlefield reconnaissance. However, the misuse of drones has introduced significant security threats, necessi…

Also available via: Institute of Electrical and Electronics Engineers

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openalexSustainability2024-07-30Cited by 26

Balancing Technological Innovation and Environmental Sustainability: A Lifecycle Analysis of 6G Wireless Communication Technology

Dharmendra Chauhan, Hiren Mewada, Vishva Gondalia, Faris A. Almalki, Sagarkumar Patel, Hardik Modi, et al.

Wireless communication has revolutionized the evolution of humankind. The rapid growth and development of mobile communication has created an ecosystem better than what has been before. However, issues such as ample energy consumption and resulting carbon emissions, a lack of pro…

Also available via: Multidisciplinary Digital Publishing Institute

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openalexComputers, materials & continua/Computers, materials & continua (Print)2024-01-01Cited by 4

Physical Layer Security of 6G Vehicular Networks with UAV Systems: First Order Secrecy Metrics, Optimization, and Bounds

Sagar Kavaiya, Hiren Mewada, Sagarkumar Patel, Dharmendra Chauhan, Faris A. Almalki, Hana Mujlid

The mobility and connective capabilities of unmanned aerial vehicles (UAVs) are becoming more and more important in defense, commercial, and research domains. However, their open communication makes UAVs susceptible to undesi... | Find, read and cite all the research you need on…

Also available via: Computers, materials & continua/Computers, materials & continua (Print)

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openalexJournal of Chemical Metrology2023-10-10Cited by 1

Simultaneous determiantion of aripiprazole and escitalopram oxalate by HPLC

Divyakumari Kiransinh Solanki, Sagarkumar P. Patel, Jasmina Surati, Ashok H Akabari, Ketan Shah, Dipansu Sahu, et al.

Simple, accurate, precise, and sensitive reverse-phase high-performance liquid chromatographic (HPLC) method was developed for the simultaneous measurement of ARI and ESC in pharmaceutical products by using a C18 column with dimensions of 250 mm x 4.6 mm and a particle size of 5…

Also available via: ACG Publications

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openalexPharmaceutical science.2023-10-09Cited by 3

Importance of Nanoparticles in Cancer Therapy and Drug Delivery: A Detailed Theory and Gaps

Sagarkumar Patel, Rachna Patel

Nanoparticles are a game-changing innovation in cancer therapy and drug delivery. Their ability to enhance drug targeting, overcome biological barriers, and minimize side effects makes them a cornerstone of modern oncology. The challenge lies in effectively distinguishing cancer…

Also available via: Pharmaceutical science.

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openalexAmerican Journal of Bioscience and Bioengineering2023-10-09

Enhanced Privacy Preservation Technique for the Multi Institutional Clinical Data Using Hybrid Feline-Storm Algorithm

Sagarkumar Patel, Rachna Patel

Today's medical research is seen to be highly dependent on data exchange; unfortunately, despite its benefits, it frequently encounters problems, particularly issues with data privacy. As a result, several methods and infrastructures have been created to ensure that patients and…

Also available via: Science Publishing Group

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openalexJournal of Phytonanotechnology and Pharmaceutical Sciences2023-09-01Cited by 9

Emerging therapies and management approaches in sickle cell disease (SCD): A critical review

Sagarkumar Patel, Rachna Patel, Srinivasa Reddy Mukkala, Ashok H Akabari

This comprehensive review delves into the intricate landscape of sickle cell disease (SCD), a global genetic disorder impacting individuals, healthcare systems, and communities.The article traces the historical origins of SCD, providing an in-depth exploration of its complex path…

Also available via: Journal of Phytonanotechnology and Pharmaceutical Sciences

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openalex2023-03-14

IMMUNOGENICITY IN PRECLINICAL DRUG DEVELOPMENT: STRATEGIES, RISKS, AND IMPLICATIONS FOR LARGE MOLECULE-BASED BIOLOGICS INCLUDING CAR T-CELL AND GENE THERAPIES

Sagarkumar Patel, Rachna Patel, Ashok H Akabari

Immunogenicity is a critical consideration in developing therapeutic agents, particularly in large molecule-based biologics, CAR T-cell therapies, and gene therapies. This comprehensive review delves into the multifaceted landscape of immunogenicity, elucidating its definition an…

Also available via: OpenAlex

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openalexJournal of Information Security2023-01-01

An Extensive Study and Review of Privacy Preservation Models for the Multi-Institutional Data

Sagarkumar Patel, Rachna Patel, Ashok Akbari, Srinivasa Reddy Mukkala

The deep learning models hold considerable potential for clinical applications, but there are many challenges to successfully training deep learning models. Large-scale data collection is required, which is frequently only possible through multi-institutional cooperation. Buildin…

Also available via: Scientific Research Publishing

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openalexResearch Square2022-08-22Cited by 1

Design of novel Channel Propagation model for underwater acoustic wireless communication inside a tank

Sweta S Panchal, Sagarkumar Patel, Sandipkumar Panchal, Jayesh Pabari

Abstract The absorption of underwater acoustic signal travelling in tank filled with water having saturation of sodium chloride is demonstrated by model developed specifically for attenuation. The simulation results of developed model for attenuation is performed using soft compu…

Also available via: Research Square

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openalexEuropean Journal of Pharmaceutical Sciences2021-12-28Cited by 41

Novel imidazopyrimidines-based molecules induce tetramerization of tumor pyruvate kinase M2 and exhibit potent antiproliferative profile

Sagarkumar Patel, Christoph Globisch, Priyanka Pulugu, Prasoon Kumar, Alok Jain, Amit Shard

Discovery of novel and potent lead molecules for the specific therapeutic targets by de novo drug design is still in infancy. Here, we disclose the unprecedented development of imidazopyri(mi)dine-based tumor pyruvate kinase M2 (PKM2) modulators by subsequent link and grow strate…

Also available via: Elsevier BV

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openalexAlexandria Engineering Journal2021-12-17Cited by 67

UWB CPW fed 4-port connected ground MIMO antenna for sub-millimeter-wave 5G applications

Amit Patel, Arpan Desai, Issa Elfergani, Alpesh Vala, Hiren Mewada, Keyur Mahant, et al.

This paper embodies the design and development of a compact Coplanar Waveguide (CPW) fed connected ground Multiple- Input-Multiple-Output (MIMO) antennas operating in the sub-millimeter-wave 5G New Radio (NR) n257/n258/n261 bands. The planar geometry leads to a small and compact…

Also available via: Elsevier BV

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openalexИзвестия высших учебных заведений Радиоэлектроника2021-06-30

Схема оценивания канала для систем связи MIMO с помощью методов обобщенного разложения Холецкого и обратной подстановки

П. Саксена, Sagarkumar Patel, Дж. К. Бхалани

В статье исследована и реализована новая схема полуслепого оценивания канала для системы связи MIMO (Multiple-Input Multiple-Output) для случая канала с квазистатическим рэлеевским замиранием. В этой схеме канальная матрица H остается относительно постоянной в пределах блока. Кан…

Also available via: Igor Sikorsky Kyiv Polytechnic Institute

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openalexRadioelectronics and Communications Systems2021-06-01

Channel Estimation Scheme for MIMO Communication Using Generalized Cholesky Decomposition and Back Substitution Methods

P Saxena, Sagarkumar Patel, Jaymin Bhalani

In this article, a novel semi-blind channel estimation scheme for Multiple-Input Multiple-Output (MIMO) communication system is studied and implemented for quasi-static Rayleigh fading channel, in which channel matrix H remains relatively constant throughout the block. Channel ma…

Also available via: Pleiades Publishing

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openalexИзвестия высших учебных заведений Радиоэлектроника2021-04-30

Полуслепой анализ канала MIMO с использованием регуляризованных по Тихонову алгоритмов MMSE и MAP с QR-разложением на основе преобразования Хаусхолдера

П. Саксена, Sagarkumar Patel, Дж. К. Бхалани

В статье предложены новые полуслепые схемы оценки для канала со многими входами и многими выходами (MIMO) с рэлеевским замиранием. В данном случае, матрица канала H представлена в виде верхней треугольной матрицы R, которую можно оценить вслепую, используя, на основе преобразован…

Also available via: Igor Sikorsky Kyiv Polytechnic Institute

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openalexCell Biology and Toxicology2021-04-17

Pyruvate kinase M2 in chronic inflammations: a potpourri of crucial protein–protein interactions

Sagarkumar Patel, Anwesha Das, Payal Meshram, Ayushi Sharma, Arnab Chowdhury, Heena Jariyal, et al.

Chronic inflammation (CI) is a primary contributing factor involved in multiple diseases like cancer, stroke, diabetes, Alzheimer's disease, allergy, asthma, autoimmune diseases, coeliac disease, glomerulonephritis, sepsis, hepatitis, inflammatory bowel disease, reperfusion injur…

Also available via: Springer Science+Business Media

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openalexRadioelectronics and Communications Systems2021-04-01Cited by 3

MIMO Semi-blind Channel Estimation by using Tikhonov Regularized MMSE and MAP Algorithms with Householder Transformation based QR Decomposition

Payal Saxena, Sagarkumar Patel, Jaymin Bhalani

In this paper, we present novel semi-blind channel estimation schemes for Rayleigh fading Multi-Input Multi-Output (MIMO) channel. Here channel matrix H is decomposed as an upper triangular matrix R, which can be estimated blindly using the Householder transformation based QR dec…

Also available via: Pleiades Publishing

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openalexBiomedical Chromatography2021-02-11Cited by 15

Metabolite profiling of IMID‐2, a novel anticancer molecule of piperazine derivative: <i>In silico</i> prediction, <i>in vitro</i> and <i>in vivo</i> metabolite characterization using UPLC–QTOF–MS/MS

Niraj Kumar Panday, Disha Thakkar, Sagarkumar Patel, Amit Shard, Pinaki Sengupta

IMID-2, a newly identified piperazine-based anticancer molecule, has been shown to be cytotoxic against various cancer cell lines. The primary aim of this research was to identify and characterize possible metabolites of the molecule formed during biotransformation. A metabolite…

Also available via: Wiley

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openalexRSC Medicinal Chemistry2021-01-01Cited by 41

Tumor pyruvate kinase M2 modulators: a comprehensive account of activators and inhibitors as anticancer agents

Bhagyashri Rathod, Shivam Chak, Sagarkumar Patel, Amit Shard

Pyruvate kinase M2 (PKM2) catalyzes the conversion of phosphoenolpyruvate (PEP) to pyruvate. It plays a central role in the metabolic reprogramming of cancer cells and is expressed in most human tumors. It is essential in indiscriminate proliferation, survival, and tackling apopt…

Also available via: Royal Society of Chemistry

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openalexИзвестия высших учебных заведений Радиоэлектроника2020-02-24Cited by 1

Характеристики неортогонального STBC при полной скорости работы в системах MIMO с пространственной корреляцией

Sagarkumar Patel, Джамин К. Бхалани, Indrajit N. Trivedi

Пространственная корреляция является одним из факторов ухудшения работы реальных систем беспроводной связи со многими входами и многими выходами MIMO (Multiple Input Multiple Output). Важно учитывать пространственную корреляцию между антеннами в реальной системе связи на обеих ст…

Also available via: Igor Sikorsky Kyiv Polytechnic Institute

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openalexRadioelectronics and Communications Systems2020-02-01Cited by 7

Performance of Full Rate Non-Orthogonal STBC in Spatially Correlated MIMO Systems

Sagarkumar Patel, Jaymin Bhalani, Y. N. Trivedi

Spatial correlation is a crucial impairment for practical Multiple Input Multiple Output (MIMO) wireless communication systems. It is important to consider spatial correlation between antennas in actual communication scenario at both sides, i.e. transmit and receive side. Further…

Also available via: Pleiades Publishing

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openalexJournal of Drug Delivery and Therapeutics2020-01-01

Computer Assisted Design, Synthesis and Biological Evaluation of Thiazole Based Molecules as Bcl2 Inhibitors

Sagarkumar Patel

Introduction: With the emergence of chemo-resistance and vast cancer types, quest to design novel and potent anticancer molecules is always a priority to enrich the armamentarium of medicinal chemists. The antiapoptotic Bcl-2 proteins are significantly over expressed in several t…

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openalexIndian Journal of Science and Technology2017-03-01Cited by 1

Performance of LTE-A Full Rate and Full Diversity STBC under Real Scattered Environment

Sagarkumar Patel, Jaymin Bhalani, Y.P. Kosta

Objectives/Background: In Long Term Evaluation- Advance (LTE-A), there are different specialized elements accessible like odd time slots transmission, use of adaptive modulation etc. Notwithstanding, the BER performance analysis is required in genuine scattered environment like s…

Also available via: Indian Society for Education and Environment

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