openalexbioRxiv (Cold Spring Harbor Laboratory)2026-07-23
Towards interoperable modeling of toehold-mediated strand exchange circuits across DNA nanotechnology and engineering biology
Zoila Jurado, Geoffrey J. Taghon, Samuel W. Schaffter
Originally developed for DNA nanotechnology, toehold-mediated strand exchange (TMSE) circuits are gaining traction in synthetic biology due to their high programmability, seamless integration with biological components, and robust operation across diverse environments and cell ty…