arxivstat.MEstat.ML2026-07-31
Longitudinal Adaptive Experimental Design for Learning Multiple Target Estimands with Semiparametric Efficient Inference
Wenxin Zhang, Mark van der Laan
Adaptive designs are increasingly used in clinical trials and digital experiments to improve estimation efficiency by updating treatment randomization probabilities as data accumulate. While most existing work focuses on settings with a single-stage treatment, adaptive designs fo…