crossrefInternational Journal of Molecular Sciences2026-06-18
Ensemble Machine Learning- and Deep Learning-Driven Identification and Validation of Sennidin B as a Novel Dipeptidyl Peptidase-4 Inhibitor
Shahid Ali, Sibhghatulla Shaikh, Jeong Ho Lim, Eun Ju Lee, Inho Choi
Dipeptidyl peptidase-4 (DPP-4) is a key therapeutic target for type 2 diabetes (T2D). Several synthetic anti-DPP-4 drugs are currently available for the treatment of T2D; however, the need for safe and effective therapies remains unmet due to the side effects associated with exis…