openalexFrontiers in Immunology2026-07-24
Structural quality-tier assessment for TCR-pMHC functional enrichment
Alex Ascunce-París, Miguel Romero‐Durana, Alfonso Valencia, Roc Farriol-Duran, Vı́ctor Guallar
T cell receptor (TCR) recognition of peptide-MHC complexes (pMHCs) is central to adaptive immunity. Structural insights into TCR-pMHC interactions are critical for understanding antigen specificity and T-cell function. However, progress remains limited by the scarcity of experime…