openalexFrontiers in Microbiology2026-07-23
Omics data in relative values are almost subcompositionally coherent
Marina Martínez-Álvaro, Michael Greenacre, A. Blasco
Introduction Omics data are compositional and often expressed as relative abundances after total sum scaling normalization. An important statistical issue with compositional data is the lack of subcompositional coherence, meaning that relative abundances change when data are re-n…