openalexFrontiers in Immunology2026-07-24
Enhanced type I interferon signature in primary APS patients is associated with thrombocytopenia
Sophie Scholz, Eduard Nitschke, L.S. Dreveton, Annika Wiedemann, Beniam Assefa, Franziska Szelinski, et al.
Introduction Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by thrombotic events and/or obstetric complications due to persistent antiphospholipid antibodies. Type I interferon (IFN) upregulation has been identified as a potential contributor to the patho…