crossrefMetabolites2025-11-01Cited by 1
Identification of a Novel Lipidomic Biomarker for Hepatocyte Carcinoma Diagnosis: Advanced Boosting Machine Learning Techniques Integrated with Explainable Artificial Intelligence
Fatma Hilal Yagin, Cemil Colak, Fahaid Al-Hashem, Sarah A. Alzakari, Amel Ali Alhussan, Mohammadreza Aghaei
Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, often diagnosed at late stages due to the limited sensitivity of current screening tools. This study explores whether blood-based lipidomic profiling, combined with explainable ar…