CORTEXA
← Browse
arxivstat.MLcs.LGq-bio.BM2026-07-06

Geometric Causal Models

Eli N. Weinstein, David M. Blei

Scientists often seek to draw causal inferences from structured data that is not independently and identically distributed, such as spatial data, network data, or molecular data. We develop geometric causal models (GCMs), a framework for causal inference from dependent data that exploits underlying symmetries of the data generating process. For example, in spatial data, we consider processes that are symmetric under translations, or in graph data, symmetric under permutations of the nodes. We show how symmetries, formalized with group theory, can enable causal identification and estimation. We deploy ergodic theory for amenable groups to establish identification, and combine geometric deep learning with scalable Bayesian inference for estimation. We recover i.i.d. causal models and do-calculus when the data is a sequence and the symmetry is permutation equivariance, and find novel types of causal models when we use alternate structures and symmetries. As an example, we construct a causal model that satisfies the symmetries of DNA. This GCM enables new estimators for the effects of genetic variation, combining deep functional genomics models to describe outcomes and DNA language models to describe propensities. We illustrate on semisynthetic data.

View free PDFSource page

Related papers

arxivcs.LGcs.AIq-bio.BMstat.ML2026-07-01

Active-GRPO: Adaptive Imitation and Self-Improving Reasoning for Molecular Optimization

Xuefeng Liu, Mingxuan Cao, Qinan Huang, Thomas Brettin, Rick Stevens, Le Cong

Scientific reasoning is an increasingly important capability of large language models, yet improving the robustness and efficiency of training such reasoning remains a key open challenge. We study this problem in instruction-based molecular optimization, where answer-only supervi…

View free PDFSource page
arxivcs.LGstat.ML2026-07-13

DAG-FM: A Foundation Model for Causal Discovery under Heterogeneous Causal Mechanisms

Yikang Chen, Zhengkang Guan, Haoyuan Qian, Peng Cui, Yi Yang, Kun Kuang

Causal discovery from observational tabular data remains fundamentally challenging, primarily due to the heterogeneity of underlying causal mechanisms and the high-dimensional combinatorial search space of Directed Acyclic Graphs (DAGs). In this paper, we propose \textbf{DAG-FM},…

View free PDFSource page
arxivcs.LGcs.AIstat.ML2026-07-13

CDFM: Towards a General-Purpose Causal Discovery Foundation Model

Jie Qiao, Ruichu Cai, Zijian Li, Weilin Chen, Pengfei Hua, Boyan Xu, et al.

Causal discovery, the process of recovering underlying causal structures from observational data, is a fundamental pursuit across scientific disciplines. Over the past decades, numerous algorithms have been developed to tackle this challenge through workflows tailored to the spec…

View free PDFSource page
arxivcs.LGstat.ML2026-07-05

A Unified Framework for In-Context Learning with Causal and Masked Language Models

Chenrui Liu, Chuanlong Xie, Falong Tan, Yicheng Zeng, Lixing Zhu

In-context learning (ICL) has emerged as a central capability of pretrained language models, yet its theoretical analysis has focused primarily on causal language models trained by left-to-right autoregressive prediction, such as GPT-style models. Masked language models instead r…

View free PDFSource page
arxivcs.CLcs.AIcs.LGstat.ML2026-07-05

CausalGame: Benchmarking Causal Thinking of LLM Agents in Games

Zhenhao Chen, Yongqiang Chen, Chenxi Liu, Junchi Yu, Xiangchen Song, Zijian Li, et al.

Building AI Scientist agents with Large Language Models (LLMs) has recently attracted growing attention. Since scientific discovery fundamentally relies on uncovering causal relationships from observations, the capability of causal thinking, i.e., distinguishing causation from co…

View free PDFSource page
arxivcs.LGstat.ML2026-06-26

Disentangling Continuous-Time Latent Dynamics: Identifiability of Latent SDEs via Diffusion Shifts

Yuanyuan Wang, Wenjie Wang, Haoxuan Li, Mingming Gong, Kun Zhang

Causal representation learning for time series has developed strong identifiability results in discrete-time latent causal models, but identifiability in continuous-time latent stochastic differential equation (SDE) models remains largely open. We address this gap using environme…

View free PDFSource page