Quantum Adaptive Sensing for Accelerated MRI

Asmit Ganguly, Suprajit Dewanji, Chenyang Zhao, Danny J. J. Wang

Compressed sensing accelerates MRI by reconstructing images from undersampled k-space, but performance depends strongly on sampling distribution. We propose an adaptive framework that selects Cartesian phase-encode lines sequentially using a fixed-cardinality quadratic unconstrained binary optimization (QUBO) formulation. The objective combines a preference for central k-space, signal-energy information from previously acquired measurements, and pairwise terms that encourage spatially dispersed sampling. The formulation is compatible with classical annealing and quantum-annealing hardware. Retrospective experiments used simulated eight-coil 3D MRI data; QUBO problems were solved with parallel tempering, and images were reconstructed with SENSE and total-variation regularization. At 20% and 10% sampling, the proposed method improved PSNR, SSIM, NMSE, and HFEN compared with the evaluated static Cartesian strategies, including variable-density Poisson-disc sampling, although gains varied with resolution, acceleration, and noise level. In a reduced-pool experiment, a D-Wave quantum-classical hybrid solver achieved reconstruction quality comparable to variable-density Poisson-disc sampling, demonstrating feasibility on current quantum optimization infrastructure. While these results do not establish quantum computational advantage, the direct QUBO representation provides a practical framework for adaptive MRI sampling and may benefit from future advances in quantum-annealing hardware. Prospective scanner validation and systematic quantum-classical benchmarking remain necessary.